Early Detection Research Network

Prostate

The TMPRSS2 gene was shown to be up-regulated by androgenic hormones in prostate cancer cells. TMPRSS2:ERG urine assay for prostate cancer detection is in studies in CLIA lab.
http://edrn.jpl.nasa.gov/bmdb/biomarkers/organs/969/895
Under Review
Two
Increased TMPRSS2:ERG transcript expression can be a predictor of prostate cancer. A multiplexed model including seven biomarkers (AMACR, ERG, GOLPH2, PCA3, SPINK1, TFF3, TMPRSS2:ERG) outperforms serum PSA or PCA3 alone.
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