Early Detection Research Network


This biomarker is also known as:
  • protein 2,
  • TNFAIP1,
  • B12,
  • OTTHUMP00000163324,
  • EDP1,
  • Protein B12,
  • hBACURD2,
  • MGC2317,
  • BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation,
  • tumor necrosis factor, alpha-induced protein 1,
  • Q13829,
  • Tumor necrosis factor, alpha-induced protein 1, endothelial,
  • BTB/POZ domain-containing protein TNFAIP1,
  • BACURD2,
  • B61,


The expression of this gene can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. Mouse studies suggest the expression of this gene is developmentally regulated in a tissue-specific manner. Thought to be involved in regulation of cytoskeleton structure.


There are no datasets associated with this biomarker.

QA State: Curated
Type: Protein

The following organs have data associated with this biomarker…


Phase: Two
QA State: Under Review


No additional ovarian data available.

Performance Comment

TNFAIP1 was one of 50 tumor vasculature-associated genes with transmembrane or secreted protein products identified through expression profiling of ovarian cancer vascular cells. These 50 tumor vascular markers (TVMs) also had low or no expression in normal tissues. TNFAIP1 was not in the group of 13 selected for further validation.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

No associated publications found.