Early Detection Research Network

TNFRSF1A

Aliases:
This biomarker is also known as:
  • Tumor Necrosis Factor Receptor Type I,
  • TNF-RI,
  • TNF-R1,
  • CD120a Antigen,
  • P60,
  • TNFR1,
  • TNFR60,
  • TNFRSF1A,
  • Tumor Necrosis Factor Receptor Superfamily, Member 1A,
  • P55-R,
  • Tumor Necrosis Factor Receptor Superfamily Member 1A,
  • FPF,
  • Tumor Necrosis Factor Receptor 1A Isoform Beta,
  • MS5,
  • TNFR1-D2,
  • Tumor Necrosis Factor Binding Protein 1,
  • CD120a,
  • Tumor Necrosis Factor Receptor 1,
  • P55,
  • TNFAR,
  • TNFR-I,
  • TBP1,
  • TNF-R,
  • Tumor Necrosis Factor Receptor Type 1,
  • Tumor Necrosis Factor-Alpha Receptor,
  • TNF-R55,

Description…

TNFRSF1A, one of the major receptors for the TNF-alpha, is a member of the TNF-receptor superfamily. This protein activates NF-kappaB, mediates apoptosis, and functions as a regulator of inflammation. TNFRSF1A has been shown to interact with adaptor proteins TRADD and TRAF2 and antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD). TNFRSF1A is involved in activating at least two distinct signaling cascades, apoptosis and NF-kappa-B signaling.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Protein
HGNC Name: TNFRSF1A

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.