Early Detection Research Network

TNFSF8

Aliases:
This biomarker is also known as:
  • CD30 antigen ligand,
  • tumor necrosis factor (ligand) superfamily, member 8,
  • CD153,
  • CD30L,
  • CD153 antigen,
  • TNFSF8,
  • tumor necrosis factor ligand superfamily member 8,
  • CD30 ligand,
  • CD30LG,
  • CD30-L,

Description…

TNFSF8, also known as CD30 ligand, is a cytokine belonging to the tumor necrosis factor (TNF) ligand family. TNFSF8 binds to TNFRSF8/CD30, a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. TNFSF8 has been shown to induce proliferation of T-cells. It also enhances cell proliferation of some lymphoma cell lines, and induces cell death and reduces cell proliferation of other lymphoma cell lines. There are two different isoforms encoded by two transcript variants.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Curated
Type: Protein
HGNC Name: TNFSF8

The following organs have data associated with this biomarker…

Attributes

Phase: Two
QA State: Curated
Organ-specific information for this biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.