Early Detection Research Network

TRIM22

Aliases:
This biomarker is also known as:
  • staf-50,
  • E3 ubiquitin-protein ligase TRIM22,
  • 50 kDa-stimulated trans-acting factor,
  • RING finger protein 94,
  • tripartite binding motif 22,
  • tripartite motif protein TRIM22,
  • tripartite motif-containing protein 22,
  • EC 6.3.2.-,
  • stimulated trans-acting factor (50 kDa),
  • GPSTAF50,
  • tripartite motif containing 22,
  • Staf-50,
  • STAF50,
  • Tripartite motif-containing protein 22,
  • TRIM22,
  • RNF94,
  • tripartite motif-containing 22,

Description…

From NCBI Gene: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Curated
Type: Gene
HGNC Name: TRIM22

The following organs have data associated with this biomarker…

Attributes

Phase: One
QA State: Curated
Organ-specific information for this biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.