Early Detection Research Network

XRCC5

Aliases:
This biomarker is also known as:
  • CTC Box-Binding Factor 85 KDa Subunit,
  • Ku80,
  • CTCBF,
  • G22P2,
  • Ku86,
  • CTC85,
  • Ku86 Autoantigen Related Protein 1,
  • Ku Autoantigen, 80kDa,
  • KUB2,
  • KU80,
  • XRCC5,
  • X-Ray Repair Complementing Defective Repair In Chinese Hamster Cells 5 (Double-Strand-Break Rejoining; Ku Autoantigen, 80kD),
  • ATP-Dependent DNA Helicase 2 Subunit 2,
  • X-Ray Repair Cross-Complementing Protein 5,
  • TLAA,
  • 80kDa,
  • Lupus Ku Autoantigen Protein P86,
  • 86 KDa Subunit Of Ku Antigen,
  • ATP-Dependent DNA Helicase II 80 KDa Subunit,
  • KARP1,
  • Thyroid-Lupus Autoantigen,
  • NFIV,
  • Ku Autoantigen,
  • X-Ray Repair Complementing Defective Repair In Chinese Hamster Cells 5 (Double-Strand-Break Rejoining),
  • KARP-1,
  • DNA Repair Protein XRCC5,
  • EC 3.6.4.-,
  • Nuclear Factor IV,

Description…

From NCBI Entrez Gene: The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Curated
Type: Protein
HGNC Name: XRCC5

The following organs have data associated with this biomarker…

Attributes

Phase: One
QA State: Curated
Organ-specific information for this biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.