Early Detection Research Network
Team Project

Pancreatic Reference Set Application: Ivan Blasutig-University of Toronto (2014)

Pancreatic Ref Set App: Blasutig (2014)
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Blasutig, IvanUniversity of Toronto
Feng, ZidingFred Hutchinson Cancer Research Center
CA19-9, CA125, CUZD16, LAMC2, AGR2, SYCN, and Reg1B
No design specified.
Proteomics
G.I. and Other Associated Cancers Research Group

The primary objective of this study is to independently validate a panel of serum biomarkers for the early detection of pancreatic ductal adenocarcinoma (PDAC). The biomarkers were identified in various discovery studies performed in our laboratory1-6. We hypothesize that our candidate biomarkers can be used as a panel that will perform better than CA19.9 alone for the early detection of PDAC. Such a panel has the potential to lead to improved patient outcomes by enabling patients to receive treatment as early as possible.

We hypothesize that our candidate biomarkers can be used as a panel that will perform better than CA19.9 alone for the early detection of PDAC
Comparisons of marker levels between groups were performed using the Mann Whitney-Wilcoxon test. Mean level comparisons were performed using a t-test and/or an ANOVA test.

There are currently no biomarkers annotated for this protocol.

No datasets are currently associated with this protocol.