Early Detection Research Network
Team Project

Breast Reference Set Application: Chris Li-FHCRC (2015)

Breast Ref Set App: Li (2015)
403
Feng, ZidingFred Hutchinson Cancer Research Center
No design specified.
UNKNOWN
Breast and Gynecologic Cancers Research Group

We propose to evaluate nine candidate biomarkers for ER+ breast cancer in samples from the EDRN Breast Cancer Reference Set. These biomarkers have been preliminarily validated in preclinical samples. The intended clinical applications of these markers are to: 1. Inform timing of a subsequent mammogram in women with a negative screening mammogram; 2. Inform continuation of mammographic screening among women 75-79 years; 3. Prioritize women who should be screened with mammography in areas with limited resources. Testing the reference samples would further expedite addressing these intended clinical applications by providing further validation data to support requests for samples from other sources for further Phase 3 evaluation (e.g., WHI, PLCO, and samples collected at the time of mammographic screening from the University of Toronto and UCSF).

There are currently no biomarkers annotated for this protocol.

No datasets are currently associated with this protocol.