Early Detection Research Network

Novel approaches to study immune responses to post translational modifications for cancer detection

AGPA in cancers
420
LaBaer, JoshuaArizona State University

No coordinating investigator defined.

No design specified.
Proteomics
Breast and Gynecologic Cancers Research Group
1

We propose to develop a BDL to discover immune-based biomarkers for the detection of breast cancers, based on fundamental tumor-specific changes in protein glycosylation.

Aim 1. Development a multiplexed platform to produce O-glycosylated proteins Aim 2. Proteome scale glycoprotein array development and production Aim 3. Identification of anti-glycoprotein antibody (TAAb-AGP) biomarkers in breast cancer
Protein array and ELISA

There are currently no biomarkers annotated for this protocol.

No datasets are currently associated with this protocol.