Early Detection Research Network

Zhang, Hui L.

Contact Information

Email: mailto:hzhang32@jhmi.edu
Fax: 443-287-6388
1747
EDRN Principal Investigator
None given

To update contact information, please visit the Data Management and Coordinating Center.

Open Protocols

Protocol Name Biomarkers Datasets
Glycoprotein Biomarkers for the Early Detection of Aggressive Prostate Cancer 0 0
PCA-3 Reference Set Application: Zhang/Johns Hopkins: Glycoprotein Biomarkers for the Early Detection of Aggressive Prostate Cancer 0 0
Prostate-Specific Glycoproteins for Early Detection of Prostate Cancer 0 0

Closed Protocols

No closed protocols.

Publications

Publication Name PubMed ID Journal
A Novel Quantitative Multiplex Tissue Immunoblotting for Biomarkers Predicts a Prostate Cancer Aggressive Phenotype. 26404961 Cancer Epidemiol. Biomarkers Prev.
An Integrated Workflow for Global, Glyco-, and Phospho-proteomic Analysis of Tumor Tissues. 31859488 Anal. Chem.
Analysis of N-glycoproteins using genomic N-glycosite prediction. 24164404 J. Proteome Res.
Characterization of disease-associated N-linked glycoproteins. 23255236 Proteomics
Chemoenzymatic method for glycomics: Isolation, identification, and quantitation. 26390280 Proteomics
Classification of Tandem Mass Spectra for Identification of N- and O-linked Glycopeptides. 27869200 Sci Rep
Comparison of Enrichment Methods for Intact N- and O-Linked Glycopeptides Using Strong Anion Exchange and Hydrophilic Interaction Liquid Chromatography. 29016103 Anal. Chem.
Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. 26571101 Nat. Biotechnol.
Comprehensive Glycoproteomic Analysis of Chinese Hamster Ovary Cells. 30457839 Anal. Chem.
Deciphering the Roles of N-Glycans on Collagen-Platelet Interactions. 31055923 J. Proteome Res.
Detection and verification of glycosylation patterns of glycoproteins from clinical specimens using lectin microarrays and lectin-based immunosorbent assays. 21975078 Anal. Chem.
Detection of aggressive prostate cancer associated glycoproteins in urine using glycoproteomics and mass spectrometry. 27749016 Proteomics
Development of a glycoproteomic strategy to detect more aggressive prostate cancer using lectin-immunoassays for serum fucosylated PSA. 30996714 Clin Proteomics
Epithelium percentage estimation facilitates epithelial quantitative protein measurement in tissue specimens. 24289299 Clin Proteomics
Expression of P40 and P63 in lung cancers using fine needle aspiration cases. Understanding clinical pitfalls and limitations. 27699149 J Am Soc Cytopathol
Glycan analysis by isobaric aldehyde reactive tags and mass spectrometry. 23895018 Anal. Chem.
Glycan analysis by reversible reaction to hydrazide beads and mass spectrometry. 22304307 Anal. Chem.
GlycoFish: a database of zebrafish N-linked glycoproteins identified using SPEG method coupled with LC/MS. 21591763 Anal. Chem.
Glycomic analysis by glycoprotein immobilization for glycan extraction and liquid chromatography on microfluidic chip. 24111616 Anal. Chem.
Glycomic analysis of glycans released from glycoproteins using chemical immobilization and mass spectrometry. 25205566 Curr Protoc Chem Biol
Glycomic analysis using glycoprotein immobilization for glycan extraction. 23688297 Anal. Chem.
Glycoproteins identified from heart failure and treatment models. 25141849 Proteomics
Glycoproteomic analysis of bronchoalveolar lavage (BAL) fluid identifies tumor-associated glycoproteins from lung adenocarcinoma. 23802180 J. Proteome Res.
Glycoproteomic analysis of prostate cancer tissues by SWATH mass spectrometry discovers N-acylethanolamine acid amidase and protein tyrosine kinase 7 as signatures for tumor aggressiveness. 24741114 Mol. Cell Proteomics
Glycoproteomics for prostate cancer detection: changes in serum PSA glycosylation patterns. 19035787 J. Proteome Res.
Glycoproteomics using fluid-based specimens in the discovery of lung cancer protein biomarkers: promise and challenge. 23112109 Proteomics Clin Appl
GPQuest: A Spectral Library Matching Algorithm for Site-Specific Assignment of Tandem Mass Spectra to Intact N-glycopeptides. 25945896 Anal. Chem.
High-throughput analysis of N-glycans using AutoTip via glycoprotein immobilization. 28860471 Sci Rep
Identification and Validation of Atypical N-Glycosylation Sites. 26593774 Anal. Chem.
Identification of glycoproteins containing specific glycans using a lectin-chemical method. 25837443 Anal. Chem.
Identification of glycoproteins associated with different histological subtypes of ovarian tumors using quantitative glycoproteomics. 22113853 Proteomics
Identification of glycoproteins associated with HIV latently infected cells using quantitative glycoproteomics. 27195445 Proteomics
Identification, prioritization, and evaluation of glycoproteins for aggressive prostate cancer using quantitative glycoproteomics and antibody-based assays on tissue specimens. 23716368 Proteomics
Inhibition of protein carbamylation in urea solution using ammonium-containing buffers. 24161613 Anal. Biochem.
Integrated glycoprotein immobilization method for glycopeptide and glycan analysis of cardiac hypertrophy. 26378618 Anal. Chem.
Intranuclear Inclusions in Conventional Clear Cell Renal Cell Carcinoma (ccRCC): Diagnosis and Differential Diagnosis. 31565700 Arch Urol Res
M2Lite: An Open-source, Light-weight, Pluggable and Fast Proteome Discoverer MSF to mzIdentML Tool. 25346941 J Bioinform
Mapping human N-linked glycoproteins and glycosylation sites using mass spectrometry. 31831916 Trends Analyt Chem
Mapping the O-glycoproteome using site-specific extraction of O-linked glycopeptides (EXoO). 30459171 Mol. Syst. Biol.
Mass spectrometric analysis of sialylated glycans with use of solid-phase labeling of sialic acids. 23445396 Anal. Chem.
Mass spectrometric protein maps for biomarker discovery and clinical research. 24138574 Expert Rev. Mol. Diagn.
Modification of Sialic Acids on Solid Phase: Accurate Characterization of Protein Sialylation. 28505427 Anal. Chem.
Multiplexed Targeted Mass Spectrometry-Based Assays for the Quantification of N-Linked Glycosite-Containing Peptides in Serum. 26451657 Anal. Chem.
Overexpression of α (1,6) fucosyltransferase in the development of castration-resistant prostate cancer cells. 29339807 Prostate Cancer Prostatic Dis.
Overexpression of Exportin-5 Overrides the Inhibitory Effect of miRNAs Regulation Control and Stabilize Proteins via Posttranslation Modifications in Prostate Cancer. 28881308 Neoplasia
Physiologic and pathophysiologic consequences of altered sialylation and glycosylation on ion channel function. 24971539 Biochem. Biophys. Res. Commun.
Platelet glycoproteins associated with aspirin-treatment upon platelet activation. 27452734 Proteomics
Proteomic analysis of Chinese hamster ovary cells. 22971049 J. Proteome Res.
Proteomics analyses of prostate cancer cells reveal cellular pathways associated with androgen resistance. 28116790 Proteomics
Quantitative glycoproteomic analysis of optimal cutting temperature-embedded frozen tissues identifying glycoproteins associated with aggressive prostate cancer. 21780747 Anal. Chem.
Quantitative proteomic analysis of ovarian cancer cells identified mitochondrial proteins associated with Paclitaxel resistance. 21113235 Proteomics Clin Appl
Reanalysis of Global Proteomic and Phosphoproteomic Data Identified a Large Number of Glycopeptides. 29741879 Anal. Chem.
Simple Tip-Based Sample Processing Method for Urinary Proteomic Analysis. 30924636 Anal. Chem.
Simultaneous analyses of N-linked and O-linked glycans of ovarian cancer cells using solid-phase chemoenzymatic method. 28100988 Clin Proteomics
Simultaneous analysis of glycosylated and sialylated prostate-specific antigen revealing differential distribution of glycosylated prostate-specific antigen isoforms in prostate cancer tissues. 21141837 Anal. Chem.
Simultaneous quantification of N- and O-glycans using a solid-phase method. 28518173 Nat Protoc
Site-Specific Fucosylation Analysis Identifying Glycoproteins Associated with Aggressive Prostate Cancer Cell Lines Using Tandem Affinity Enrichments of Intact Glycopeptides Followed by Mass Spectrometry. 28627880 Anal. Chem.
Site-Specific Profiling of Serum Glycoproteins Using N-Linked Glycan and Glycosite Analysis Revealing Atypical N-Glycosylation Sites on Albumin and α-1B-Glycoprotein. 29671580 Anal. Chem.
Solid phase extraction of N-linked glycopeptides using hydrazide tip. 24079330 Anal. Chem.
Solid-phase glycan isolation for glycomics analysis. 23090885 Proteomics Clin Appl
Targeted analyte detection by standard addition improves detection limits in matrix-assisted laser desorption/ionization mass spectrometry. 22877355 Anal. Chem.
Targeted proteomic assays for the verification of global proteomics insights. 27565203 Expert Rev Proteomics
Targeted proteomics: a bridge between discovery and validation. 25348939 Expert Rev Proteomics
Tissue proteomics using chemical immobilization and mass spectrometry. 25283129 Anal. Biochem.
Tyramide signal amplification for antibody-overlay lectin microarray: a strategy to improve the sensitivity of targeted glycan profiling. 21133419 J. Proteome Res.
XGlycScan: An Open-source Software For N-linked Glycosite Assignment, Quantification and Quality Assessment of Data from Mass Spectrometry-based Glycoproteomic Analysis. 25346946 MOJ Proteom Bioinform

To update protocols, publications, biomarkers, or science data, please contact the Informatics Center.